Science

The applied technology is based on the fact that diseases are reflected by the protein composition of body fluids. World wide this knowledge is routinely used for diagnostic purposes. The technology allows not only the analysis of a single protein biomarker, but the simultaneous analysis of hundreds of biomarkers in a single analytical step.

The particular technology uses the innovative coupling of two analytical methods capillary electrophoresis and mass spectrometry (CE-MS). The urinary proteins are separated in an electric field by the capillary electrophoresis and are subsequently analysed in a mass spectrometer; a molecular balance that measures the molecular weight of the proteins.

The obtained data sets of more than 1 GB volume are processed and evaluated using special software solutions and are digitally compared with a disease specific biomarker profile to identify patients at high risk.